The Caporarello Lab (nickname: CAP LAB) is located at Loyola University Chicago, Center for Translational Research and Education. Our research is focused on understanding mechanisms of lung injury and repair in the context of chronic respiratory diseases, such as Idiopathic Pulmonary Fibrosis.
The lab uses preclinical mouse models to study vascular responses to lung injury, and human lung samples to translate preclinical findings into understanding of human disease progression. The goal is to translate basic understanding of vascular pathophysiology into novel interventions for chronic lung diseases.
The lab has also interest in identifying endothelial derived signaling molecules  and circulating factors central to lung repair, that might be missing or dysregulated with lung aging and disease, including connective tissue diseases associated with Pulmonary Fibrosis.